Role of ADP-Ribosyltransferase Activity of Pertussis Toxin in Toxin-Adhesin Redundancy with Filamentous Hemagglutinin during Bordetella pertussis Infection

Pertussis toxin (PT) and filamentous hemagglutinin (FHA) are two major virulence factors of Bordetella pertussis. FHA is the main adhesin, whereas PT is a toxin with an A-B structure, in which the A protomer expresses ADP-ribosyltransferase activity and the B moiety is responsible for binding to the...

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Hlavní autoři: Alonso, Sylvie, Pethe, Kévin, Mielcarek, Nathalie, Raze, Dominique, Locht, Camille
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC98732/
https://ncbi.nlm.nih.gov/pubmed/11553541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.10.6038-6043.2001
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