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Escherichia coli Cytotoxic Necrotizing Factor and Pasteurella multocida Toxin Induce Focal Adhesion Kinase Autophosphorylation and Src Association

Cytotoxic necrotizing factor 1 and Pasteurella multocida toxin induced dose- and time-dependent increases in focal adhesion kinase (FAK) Tyr(397) phosphorylation in Swiss 3T3 cells. FAK autophosphorylation was sensitive to inhibitors of p160/ROCK and coincided with the formation of stable complexes...

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Bibliografiske detaljer
Main Authors: Thomas, Warren, Pullinger, Gillian D., Lax, Alistair J., Rozengurt, Enrique
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98716/
https://ncbi.nlm.nih.gov/pubmed/11500476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.9.5931-5935.2001
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