Fas/Fas Ligand System Mediates Epithelial Injury, but Not Pulmonary Host Defenses, in Response to Inhaled Bacteria

The Fas/Fas ligand (FasL) system has been implicated in alveolar epithelial cell apoptosis during pulmonary fibrosis and acute respiratory distress syndrome. However, Fas ligation can also lead to cell activation and cytokine production. The goal of this study was to determine the role of the Fas/Fa...

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Main Authors: Matute-Bello, Gustavo, Frevert, Charles W., Liles, W. Conrad, Nakamura, Morio, Ruzinski, John T., Ballman, Kimberly, Wong, Venus A., Vathanaprida, Charie, Martin, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Host Response and Inflammation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC98694/
https://ncbi.nlm.nih.gov/pubmed/11500454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.9.5768-5776.2001
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