Hydrolysis of Interleukin-12 by Porphyromonas gingivalis Major Cysteine Proteinases May Affect Local Gamma Interferon Accumulation and the Th1 or Th2 T-Cell Phenotype in Periodontitis

Porphyromonas gingivalis cysteine proteinases (gingipains) have been associated with virulence in destructive periodontitis, a disease process variously considered to represent an unregulated stimulation of either T helper type 1 (Th1)- or Th2-type cells. Critical in maintaining Th1 activity is the...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Yun, Peter L. W., Decarlo, Arthur A., Collyer, Charles, Hunter, Neil
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2001
Fag:	Host Response and Inflammation
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98681/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11500441/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.9.5650-5660.2001
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