T-Cell Reactivity against Streptococcal Antigens in the Periphery Mirrors Reactivity of Heart-Infiltrating T Lymphocytes in Rheumatic Heart Disease Patients

T-cell molecular mimicry between streptococcal and heart proteins has been proposed as the triggering factor leading to autoimmunity in rheumatic heart disease (RHD). We searched for immunodominant T-cell M5 epitopes among RHD patients with defined clinical outcomes and compared the T-cell reactivit...

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Detalhes bibliográficos
Main Authors: Guilherme, Luiza, Oshiro, Sandra E., Faé, Kellen C., Cunha-Neto, Edécio, Renesto, Guilherme, Goldberg, Anna C., Tanaka, Ana C., Pomerantzeff, Pablo M. A, Kiss, Maria H., Silva, Clóvis, Guzman, Fanny, Patarroyo, Manuel E., Southwood, Scott, Sette, Alessandro, Kalil, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98644/
https://ncbi.nlm.nih.gov/pubmed/11500404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.9.5345-5351.2001
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