Construction and Characterization of Genetically Defined aro omp Mutants of Enterotoxigenic Escherichia coli and Preliminary Studies of Safety and Immunogenicity in Humans

Enterotoxigenic Escherichia coli (ETEC) is a leading cause of diarrhea in travelers to countries where the disease is endemic and causes a major disease burden in the indigenous population, particularly children. We describe here the generation and preclinical characterization of candidate strains o...

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Detalhes bibliográficos
Main Authors: Turner, Arthur K., Terry, Tamsin D., Sack, David A., Londoño-Arcila, Patricia, Darsley, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98589/
https://ncbi.nlm.nih.gov/pubmed/11447175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.8.4969-4979.2001
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