Hyphae and Yeasts of Candida albicans Differentially Regulate Interleukin-12 Production by Human Blood Monocytes: Inhibitory Role of C. albicans Germination

The role of Candida albicans yeast-to-hypha transition in interleukin-12 (IL-12) production by monocytes was investigated. Germinating C. albicans not only failed to induce IL-12 p70 but also suppressed IL-12 production induced by heat-killed C. albicans. Comparison of the abilities of germinating C...

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Main Authors: Liu, Liming, Kang, Kefei, Takahara, Masakazu, Cooper, Kevin D., Ghannoum, Mahmoud A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98552/
https://ncbi.nlm.nih.gov/pubmed/11402019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.7.4695-4697.2001
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