Brucella abortus Cyclic β-1,2-Glucan Mutants Have Reduced Virulence in Mice and Are Defective in Intracellular Replication in HeLa Cells

Null cyclic β-1,2-glucan synthetase mutants (cgs mutants) were obtained from Brucella abortus virulent strain 2308 and from B. abortus attenuated vaccinal strain S19. Both mutants show greater sensitivity to surfactants like deoxycholic acid, sodium dodecyl sulfate, and Zwittergent than the parental...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Briones, Gabriel, Iñón de Iannino, Nora, Roset, Mara, Vigliocco, Ana, Paulo, Patricia Silva, Ugalde, Rodolfo A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Bacterial Infections
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98529/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11401996/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.7.4528-4535.2001
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