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Distinct Cytokine Regulation by Cholera Toxin and Type II Heat-Labile Toxins Involves Differential Regulation of CD40 Ligand on CD4(+) T Cells

Cholera toxin (CT) and the type II heat-labile enterotoxins (HLT) LT-IIa and LT-IIb act as potent systemic and mucosal adjuvants and induce distinct T-helper (Th)-cell cytokine profiles. In the present study, CT and the type II HLT were found to differentially affect cytokine production by anti-CD3-...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Martin, Michael, Metzger, Daniel J., Michalek, Suzanne M., Connell, Terry D., Russell, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98523/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11401990/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.7.4486-4492.2001
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