Induction of Autoimmune Valvular Heart Disease by Recombinant Streptococcal M Protein

Rheumatic heart disease is an autoimmune sequela of group A streptococcal infection. Previous studies have established that streptococcal M protein is structurally and immunologically similar to cardiac myosin, a well-known mediator of inflammatory heart disease. In this study, we investigated the h...

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Autori principali: Quinn, Anthony, Kosanke, Stanley, Fischetti, Vincent A., Factor, Stephen M., Cunningham, Madeleine W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Host Response and Inflammation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC98471/
https://ncbi.nlm.nih.gov/pubmed/11349078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.6.4072-4078.2001
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