Helicobacter pylori Activates the Cyclin D1 Gene through Mitogen- Activated Protein Kinase Pathway in Gastric Cancer Cells

Helicobacter pylori induces cellular proliferation in host cells, but the mechanism remains unclear. Thus, we examined the effect of H. pylori on cyclin D1, an important regulator of the cell cycle, especially in relation to intracellular signaling pathways. In a Northern blot analysis, cyclin D1 tr...

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Main Authors: Hirata, Yoshihiro, Maeda, Shin, Mitsuno, Yuzo, Akanuma, Masao, Yamaji, Yutaka, Ogura, Keiji, Yoshida, Haruhiko, Shiratori, Yasushi, Omata, Masao
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC98458/
https://ncbi.nlm.nih.gov/pubmed/11349065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.6.3965-3971.2001
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