Diepitopic Construct of Functionally and Epitopically Complementary Peptides Enhances Immunogenicity, Reactivity with Glucosyltransferase, and Protection from Dental Caries

Coimmunization with peptide constructs from catalytic (CAT) and glucan-binding (GLU) domains of glucosyltransferase (GTF) of mutans streptococci has resulted in enhanced levels of antibody to the CAT construct and to GTF. We designed and synthesized a diepitopic construct (CAT-GLU) containing two co...

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Detalhes bibliográficos
Main Authors: Taubman, Martin A., Holmberg, Cynthia J., Smith, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98453/
https://ncbi.nlm.nih.gov/pubmed/11401956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.7.4210-4216.2001
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