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Decorin-Binding Protein A (DbpA) of Borrelia burgdorferi Is Not Protective When Immunized Mice Are Challenged via Tick Infestation and Correlates with the Lack of DbpA Expression by B. burgdorferi in Ticks

Previous studies showed that decorin-binding protein A (DbpA) of Borrelia burgdorferi was a protective immunogen in the murine model of Lyme borreliosis when mice were challenged (needle inoculated) intradermally with in vitro-cultivated spirochetes. In the present study, DbpA-immunized C3H/HeJ mice...

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Udgivet i:Infect Immun
Principais autores: Hagman, Kayla E., Yang, Xiaofeng, Wikel, Stephen K., Schoeler, George B., Caimano, Melissa J., Radolf, Justin D., Norgard, Michael V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98430/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10899883/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.8.4759-4764.2000
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