Constitutive Expression of the Vi Polysaccharide Capsular Antigen in Attenuated Salmonella enterica Serovar Typhi Oral Vaccine Strain CVD 909

Live oral Ty21a and parenteral Vi polysaccharide vaccines provide significant protection against typhoid fever, albeit by distinct immune mechanisms. Vi stimulates serum immunoglobulin G Vi antibodies, whereas Ty21a, which does not express Vi, elicits humoral and cell-mediated immune responses other...

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Main Authors: Wang, Jin Yuan, Noriega, Fernando R., Galen, James E., Barry, Eileen, Levine, Myron M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Microbial Immunity and Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC98400/
https://ncbi.nlm.nih.gov/pubmed/10899868
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