Protection against Pseudomonas aeruginosa Chronic Lung Infection in Mice by Genetic Immunization against Outer Membrane Protein F (OprF) of P. aeruginosa

The Pseudomonas aeruginosa major constitutive outer membrane porin protein OprF, which has previously been shown to be a protective antigen, was targeted as a DNA vaccine candidate. The oprF gene was cloned into plasmid vector pVR1020, and the plasmid vaccines were delivered to mice by biolistic (ge...

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Autors principals: Price, Brian M., Galloway, Darrell R., Baker, Neil R., Gilleland, Linda B., Staczek, John, Gilleland, Harry E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC98322/
https://ncbi.nlm.nih.gov/pubmed/11292786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.3510-3515.2001
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