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Escherichia coli CdtB Mediates Cytolethal Distending Toxin Cell Cycle Arrest

We previously reported that the CdtB polypeptide of Escherichia coli cytolethal distending toxin (CDT) shares significant pattern-specific homology with mammalian type I DNases. In addition, the DNase-related residues of CdtB are required for cellular toxicity. Here we demonstrate that purified CdtB...

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Publicado no:Infect Immun
Principais autores: Elwell, Cherilyn, Chao, Kinlin, Patel, Kamlesh, Dreyfus, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2001
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98302/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11292766/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.5.3418-3422.2001
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