Escherichia coli CdtB Mediates Cytolethal Distending Toxin Cell Cycle Arrest

We previously reported that the CdtB polypeptide of Escherichia coli cytolethal distending toxin (CDT) shares significant pattern-specific homology with mammalian type I DNases. In addition, the DNase-related residues of CdtB are required for cellular toxicity. Here we demonstrate that purified CdtB...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Principais autores:	Elwell, Cherilyn, Chao, Kinlin, Patel, Kamlesh, Dreyfus, Lawrence
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Assuntos:	Molecular Pathogenesis
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98302/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11292766/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.5.3418-3422.2001
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