Monoclonal Antibodies Specific for Neisseria meningitidis Group B Polysaccharide and Their Peptide Mimotopes

From five mice immunized with Escherichia coli K1 bacteria, we produced 12 immunoglobulin M hybridomas secreting monoclonal antibodies (MAbs) that bind to Neisseria meningitidis group B (NMGB). The 12 MAbs also bound the capsular polysaccharide (PS) of E. coli K1 [which, like NMGB, is α(2-8)-linked...

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Main Authors: Shin, J. S., Lin, J. S., Anderson, P. W., Insel, R. A., Nahm, M. H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98292/
https://ncbi.nlm.nih.gov/pubmed/11292756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.3335-3342.2001
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