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Gamma Interferon and Lipopolysaccharide Interact at the Level of Transcription To Induce Tumor Necrosis Factor Alpha Expression

Lipopolysaccharide (LPS) is a very potent inducer of tumor necrosis factor alpha (TNF-α) expression from monocytes and macrophages. Another inflammatory cytokine, gamma interferon (IFN-γ), can potentiate the effects of LPS, but the mechanism is not thoroughly understood. Previous reports emphasized...

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Autori principali: Lee, Julia Y., Sullivan, Kathleen E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC98233/
https://ncbi.nlm.nih.gov/pubmed/11292697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.2847-2852.2001
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