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Upregulation of Toll-Like Receptor 2 Gene Expression in Macrophage Response to Peptidoglycan and High Concentration of Lipopolysaccharide Is Involved in NF-κB Activation

Toll-like receptors 2 and 4 (TLR2 and TLR4) have been found to transduce signals of peptidoglycan (PGN) and lipopolysaccharide (LPS), respectively, for NF-κB activation. However, little is known about the expression and regulation of the TLR2 gene in monocytes/macrophages in response to the two typi...

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Main Authors: Liu, Yan, Wang, Yin, Yamakuchi, Munekazu, Isowaki, Sumikazu, Nagata, Etsuro, Kanmura, Yuichi, Kitajima, Isao, Maruyama, Ikuro
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC98226/
https://ncbi.nlm.nih.gov/pubmed/11292690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.2788-2796.2001
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