Differential Gene Expression during Meningeal-Meningococcal Interaction: Evidence for Self-Defense and Early Release of Cytokines and Chemokines

Using microarray technology, we studied the early differential expression of 3,528 genes in human meningothelial cells in response to meningococcal challenge. Thirty-two genes were up-regulated, and four were down-regulated. Those up-regulated included the tumor necrosis factor alpha, interleukin-6...

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Detalhes bibliográficos
Main Authors: Wells, Damien B., Tighe, Patrick J., Wooldridge, Karl G., Robinson, Karen, Ala' Aldeen, Dlawer A. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Molecular Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98212/
https://ncbi.nlm.nih.gov/pubmed/11254640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.4.2718-2722.2001
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