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DNA from Protozoan Parasites Babesia bovis, Trypanosoma cruzi, and T. brucei Is Mitogenic for B Lymphocytes and Stimulates Macrophage Expression of Interleukin-12, Tumor Necrosis Factor Alpha, and Nitric Oxide

The activation of innate immune responses by genomic DNA from bacteria and several nonvertebrate organisms represents a novel mechanism of pathogen recognition. We recently demonstrated the CpG-dependent mitogenic activity of DNA from the protozoan parasite Babesia bovis for bovine B lymphocytes (W....

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Udgivet i:Infect Immun
Principais autores: Shoda, Lisl K. M., Kegerreis, Kimberly A., Suarez, Carlos E., Roditi, Isabel, Corral, Ricardo S., Bertot, Gustavo M., Norimine, Junzo, Brown, Wendy C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98143/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11254571/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.4.2162-2171.2001
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