DNA Vaccines Expressing a Fusion Product of Outer Surface Proteins A and C from Borrelia burgdorferi Induce Protective Antibodies Suitable for Prophylaxis but Not for Resolution of Lyme Disease

DNA vaccines encoding the outer surface protein A (OspA) of Borrelia burgdorferi have been shown to induce protective humoral responses capable of preventing but not curing infection in mice. Subsequent studies showed that an established infection or disease could be resolved by passive transfer of...

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Detalhes bibliográficos
Main Authors: Wallich, Reinhard, Siebers, Annette, Jahraus, Oliver, Brenner, Christiane, Stehle, Thomas, Simon, Markus M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98139/
https://ncbi.nlm.nih.gov/pubmed/11254567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.4.2130-2136.2001
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