Chemokine-Dependent Neutrophil Recruitment in a Murine Model of Legionella Pneumonia: Potential Role of Neutrophils as Immunoregulatory Cells

The roles of CXC chemokine-mediated host responses were examined with an A/J mouse model of Legionella pneumophila pneumonia. After intratracheal inoculation of 10(6) CFU of L. pneumophila, the bacterial numbers in the lungs increased 10-fold by day 2; this increase was accompanied by the massive ac...

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Detalhes bibliográficos
Main Authors: Tateda, Kazuhiro, Moore, Thomas A., Newstead, Michael W., Tsai, Wan C., Zeng, Xianying, Deng, Jane C., Chen, Gina, Reddy, Raju, Yamaguchi, Keizo, Standiford, Theodore J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98125/
https://ncbi.nlm.nih.gov/pubmed/11254553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.4.2017-2024.2001
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