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Circumvention of Herd Immunity during an Outbreak of Meningococcal Disease Could Be Correlated to Escape Mutation in the porA Gene of Neisseria meningitidis

Meningococcal strains isolated during an outbreak were shown to belong to the ET-5 complex and to harbor a mutation in the VR2 region of the porA gene. They were less susceptible to the bactericidal effect of normal human serum than was the ET-5 wild-type strain. These results are of concern, as Por...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Taha, Muhamed-Kheir, Bichier, Edouard, Perrocheau, Anne, Alonso, Jean-Michel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2001
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC98115/
https://ncbi.nlm.nih.gov/pubmed/11179386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.3.1971-1973.2001
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