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Neutralization of Shiga Toxins Stx1, Stx2c, and Stx2e by Recombinant Bacteria Expressing Mimics of Globotriose and Globotetraose

Strains of Escherichia coli producing Shiga toxins Stx1, Stx2, Stx2c, and Stx2d cause gastrointestinal disease and the hemolytic-uremic syndrome in humans. We have recently constructed a recombinant bacterium which displays globotriose (the receptor for these toxins) on its surface and adsorbs and n...

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Udgivet i:Infect Immun
Principais autores: Paton, Adrienne W., Morona, Renato, Paton, James C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98114/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11179385/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.3.1967-1970.2001
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