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Legionella pneumophila Suppresses Interleukin-12 Production by Macrophages

In vitro infection of macrophages with Legionella pneumophila induced interleukin-1α (IL-1α), IL-10, monocyte chemotactic protein 1 (MCP-1), and MCP-3 but not IL-12. The lipopolysaccharide (LPS)-induced production of IL-12 was down-regulated by infection with virulent L. pneumophila, but other cytok...

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Publicado no:Infect Immun
Principais autores: Matsunaga, Kazuto, Klein, Thomas W., Newton, Catherine, Friedman, Herman, Yamamoto, Yoshimasa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2001
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98106/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11179377/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.3.1929-1933.2001
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