Recombinant Neisseria meningitidis Transferrin Binding Protein A Protects against Experimental Meningococcal Infection

To better characterize the vaccine potential of Neisseria meningitidis transferrin binding proteins (Tbps), we have overexpressed TbpA and TbpB from Neisseria meningitidis isolate K454 in Escherichia coli. The ability to bind human transferrin was retained by both recombinant proteins, enabling puri...

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Autors principals: West, David, Reddin, Karen, Matheson, Mary, Heath, Robert, Funnell, Simon, Hudson, Michael, Robinson, Andrew, Gorringe, Andrew
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC98056/
https://ncbi.nlm.nih.gov/pubmed/11179327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.3.1561-1567.2001
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