Recombinant Neisseria meningitidis Transferrin Binding Protein A Protects against Experimental Meningococcal Infection

To better characterize the vaccine potential of Neisseria meningitidis transferrin binding proteins (Tbps), we have overexpressed TbpA and TbpB from Neisseria meningitidis isolate K454 in Escherichia coli. The ability to bind human transferrin was retained by both recombinant proteins, enabling puri...

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Bibliographische Detailangaben
Hauptverfasser: West, David, Reddin, Karen, Matheson, Mary, Heath, Robert, Funnell, Simon, Hudson, Michael, Robinson, Andrew, Gorringe, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98056/
https://ncbi.nlm.nih.gov/pubmed/11179327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.3.1561-1567.2001
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