Recombinant Neisseria meningitidis Transferrin Binding Protein A Protects against Experimental Meningococcal Infection

To better characterize the vaccine potential of Neisseria meningitidis transferrin binding proteins (Tbps), we have overexpressed TbpA and TbpB from Neisseria meningitidis isolate K454 in Escherichia coli. The ability to bind human transferrin was retained by both recombinant proteins, enabling puri...

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Detalhes bibliográficos
Main Authors: West, David, Reddin, Karen, Matheson, Mary, Heath, Robert, Funnell, Simon, Hudson, Michael, Robinson, Andrew, Gorringe, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98056/
https://ncbi.nlm.nih.gov/pubmed/11179327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.3.1561-1567.2001
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