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Induction of Lysogenic Bacteriophage and Phage-Associated Toxin from Group A Streptococci during Coculture with Human Pharyngeal Cells

We found that when group A streptococci are cocultured with human pharyngeal cells, they upregulate and secrete a 25-kDa toxin, determined to be the bacteriophage-encoded streptococcal pyrogenic exotoxin C (SpeC). This prompted us to determine if the bacteriophage themselves are induced during cocul...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Broudy, Thomas B., Pancholi, Vijaykumar, Fischetti, Vincent A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98039/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11179310/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.3.1440-1443.2001
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