Mycobacterium tuberculosis 19-Kilodalton Lipoprotein Inhibits Mycobacterium smegmatis-Induced Cytokine Production by Human Macrophages In Vitro

Vaccination of mice with Mycobacterium vaccae or M. smegmatis induces some protection against M. tuberculosis challenge. The 19-kDa lipoprotein of M. tuberculosis, expressed in M. vaccae or M. smegmatis (M. smeg19kDa), abrogates this protective immunity. To investigate the mechanism of this suppress...

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Main Authors: Post, Frank A., Manca, Claudia, Neyrolles, Olivier, Ryffel, Bernhard, Young, Douglas B., Kaplan, Gilla
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Host Response and Inflammation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC98038/
https://ncbi.nlm.nih.gov/pubmed/11179309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.3.1433-1439.2001
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