Salivary Histatin 5 Is an Inhibitor of Both Host and Bacterial Enzymes Implicated in Periodontal Disease

One of the salient features of periodontitis and gingivitis is the increase in the levels of bacterial and host-derived proteolytic enzymes in oral inflammatory exudates. This study evaluated the potential of histatin 5, a 24-residue histidine-rich salivary antimicrobial protein, to inhibit these en...

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Bibliographic Details
Main Authors: Gusman, Heloisa, Travis, James, Helmerhorst, Eva J., Potempa, Jan, Troxler, Robert F., Oppenheim, Frank G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC98034/
https://ncbi.nlm.nih.gov/pubmed/11179305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.3.1402-1408.2001
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