Functional Characteristics of a Protective Monoclonal Antibody against Serotype A and C Lipooligosaccharides from Moraxella catarrhalis

A monoclonal antibody (MAb), designated MAb 8E7 (immunoglobulin G3), specific for Moraxella catarrhalis lipooligosaccharide (LOS) was evaluated for its functional activity in vitro and in a mouse model of colonization. Enzyme-linked immunosorbent assay (ELISA) demonstrated that the MAb 8E7 could be...

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Bibliographische Detailangaben
Hauptverfasser: Hu, Wei-Gang, Chen, Jing, McMichael, John C., Gu, Xin-Xing
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98028/
https://ncbi.nlm.nih.gov/pubmed/11179299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.3.1358-1363.2001
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