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Inhibition of p38 Mitogen-Activated Protein Kinase Augments Lipopolysaccharide-Induced Cell Proliferation in CD14-Expressing Chinese Hamster Ovary Cells

CD14-expressing Chinese hamster ovary (CD14-CHO) cells, established by transfection of human CD14 DNA, acquired high responsiveness to lipopolysaccharide (LPS) through membrane-bound CD14 expression. LPS induced DNA synthesis and activated a series of mitogen-activated protein (MAP) kinases, extrace...

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Autori principali: Chakravortty, Dipshikha, Kato, Yutaka, Sugiyama, Tsuyoshi, Koide, Naoki, Mu, Mya Mya, Yoshida, Tomoaki, Yokochi, Takashi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC97972/
https://ncbi.nlm.nih.gov/pubmed/11159988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.2.931-936.2001
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