Synthetic 6B Di-, Tri-, and Tetrasaccharide-Protein Conjugates Contain Pneumococcal Type 6A and 6B Common and 6B- Specific Epitopes That Elicit Protective Antibodies in Mice

The immunogenicity and protective capacity of Streptococcus pneumoniae 6B capsular polysaccharide (PS)-derived synthetic phosphate-containing disaccharide (Rha-ribitol-P-), trisaccharide (ribitol-P-Gal-Glc-), and tetrasaccharide (Rha-ribitol-P-Gal-Glc-)-protein conjugates in rabbits and mice were st...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Jansen, Wouter T. M., Hogenboom, Sietske, Thijssen, Mark J. L., Kamerling, Johannis P., Vliegenthart, Johannes F. G., Verhoef, Jan, Snippe, Harm, Verheul, André F. M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97953/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11159969/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.2.787-793.2001
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