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Mouse Toxicity and Cytokine Release by Verotoxin 1 B Subunit Mutants
The crystal structure of the verotoxin 1 (VT1) B subunit complexed with a globotriaosylceramide (Gb(3)) analogue showed the presence of three receptor binding sites per monomer. We wished to study the effects of altering the three sites, singly or in combination, on animal toxicity and cytokine indu...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC97923/ https://ncbi.nlm.nih.gov/pubmed/11119557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.1.579-583.2001 |
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