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Targeted Reduction in Expression of Trypanosoma cruzi Surface Glycoprotein gp90 Increases Parasite Infectivity

A previous study had shown that the expression of gp90, a stage-specific surface glycoprotein of Trypanosoma cruzi metacyclic trypomastigotes, is inversely correlated with the parasite's ability to invade mammalian cells. By using antisense oligonucleotides complementary to a region of the gp90 gene...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Málaga, Sergio, Yoshida, Nobuko
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2001
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97890/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11119524/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.1.353-359.2001
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