Recombinant Antigen-Enterotoxin A2/B Chimeric Mucosal Immunogens Differentially Enhance Antibody Responses and B7-Dependent Costimulation of CD4(+) T Cells

The ADP-ribosylating enterotoxins, cholera toxin (CT) and the Escherichia coli heat-labile toxin (LT-IIa), have been shown to enhance mucosal and systemic antibody (Ab) responses to coadministered antigens. The purpose of the present study was to compare the ability of the nontoxic A2/B subunits of...

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Publié dans:	Infect Immun
Auteurs principaux:	Martin, Michael, Hajishengallis, George, Metzger, Daniel J., Michalek, Suzanne M., Connell, Terry D., Russell, Michael W.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2001
Sujets:	Microbial Immunity and Vaccines
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97879/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11119513/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.1.252-261.2001
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