Vervet Monkeys Vaccinated with Killed Leishmania major Parasites and Interleukin-12 Develop a Type 1 Immune Response but Are Not Protected against Challenge Infection

Leishmania major is a protozoan parasite that causes chronic cutaneous lesions that often leave disfiguring scars. Infections in mice have demonstrated that leishmanial vaccines that include interleukin-12 (IL-12) as an adjuvant are able to induce protective immunity. In this study, we assessed the...

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Detalhes bibliográficos
Main Authors: Gicheru, Michael M., Olobo, Joseph O., Anjili, Christopher O., Orago, Alloys S., Modabber, Farrokh, Scott, Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC97878/
https://ncbi.nlm.nih.gov/pubmed/11119512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.1.245-251.2001
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