Human CD8(+) T Cells Specific for Mycobacterium tuberculosis Secreted Antigens in Tuberculosis Patients and Healthy BCG-Vaccinated Controls in The Gambia

Intracellular flow cytometry analysis of perforin production by CD8(+) T cells showed levels were greatly reduced in tuberculosis (TB) patients compared to healthy controls. Reduced cytotoxic-T-lymphocyte activity was also obtained with CD8(+) T cells from TB patients compared to healthy controls in...

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Main Authors: Smith, Steven M., Klein, Michèl R., Malin, Adam S., Sillah, Jackson, Huygen, Kris, Andersen, Peter, McAdam, Keith P. W. J., Dockrell, Hazel M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Bacterial Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC97828/
https://ncbi.nlm.nih.gov/pubmed/11083843
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