Evidence for Vaccine Synergy between Borrelia burgdorferi Decorin Binding Protein A and Outer Surface Protein A in the Mouse Model of Lyme Borreliosis

Mice immunized with either the predominantly vector-stage lipoprotein outer surface protein A (OspA) or the in vivo-expressed lipoprotein decorin binding protein A (DbpA) are protected against Borrelia burgdorferi challenge. DbpA-OspA combinations protected against 100-fold-higher challenge doses th...

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Bibliographic Details
Main Authors: Hanson, Mark S., Patel, Nita K., Cassatt, David R., Ulbrandt, Nancy D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC97733/
https://ncbi.nlm.nih.gov/pubmed/11035759
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