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Use of Pertussis Toxin Encoded by ptx Genes from Bordetella bronchiseptica To Model the Effects of Antigenic Drift of Pertussis Toxin on Antibody Neutralization

Recently, concern has been voiced about the potential effect that antigenic divergence of circulating strains of Bordetella pertussis might have on the efficacy of pertussis vaccines. In order to model antigenic drift of pertussis toxin, a critical component of many pertussis vaccines, and to examin...

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Главные авторы: Hausman, Sally Z., Burns, Drusilla L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2000
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC97675/
https://ncbi.nlm.nih.gov/pubmed/10816544
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