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Toll-Like Receptors Confer Responsiveness to Lipopolysaccharide from Porphyromonas gingivalis in Human Gingival Fibroblasts

Gingival fibroblasts produce proinflammatory cytokines in response to lipopolysaccharide (LPS) from periodontopathic bacteria. Recently it has become evident that the human homologue of Drosophila Toll can transduce intracellular signaling by LPS stimulation. Toll-like receptors (TLRs) have been ide...

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Bibliographic Details
Main Authors: Tabeta, Kouich, Yamazaki, Kazuhisa, Akashi, Sachiko, Miyake, Kensuke, Kumada, Hidefumi, Umemoto, Toshio, Yoshie, Hiromasa
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC97668/
https://ncbi.nlm.nih.gov/pubmed/10816537
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