In Vitro Resistance of Staphylococcus aureus to Thrombin-Induced Platelet Microbicidal Protein Is Associated with Alterations in Cytoplasmic Membrane Fluidity

Platelet microbicidal proteins (PMPs) are small, cationic peptides which possess potent microbicidal activities against common bloodstream pathogens, such as Staphylococcus aureus. We previously showed that S. aureus strains exhibiting resistance to thrombin-induced PMP (tPMP-1) in vitro have an enh...

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Main Authors: Bayer, Arnold S., Prasad, Rajendra, Chandra, Jyotsna, Koul, Anjni, Smriti, M., Varma, Archana, Skurray, Ronald A., Firth, Neville, Brown, Melissa H., Koo, Su-Pin, Yeaman, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Molecular and Cellular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC97641/
https://ncbi.nlm.nih.gov/pubmed/10816510
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