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Role of Hyphal Formation in Interactions of Candida albicans with Endothelial Cells

The ability to change from yeast to hyphal morphology is a major virulence determinant of Candida albicans. Mutants with defined defects in filamentation regulatory pathways have reduced virulence in mice. However, is it poorly understood why hyphal formation is critical for C. albicans to cause hem...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Phan, Quynh T., Belanger, Paul H., Filler, Scott G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC97632/
https://ncbi.nlm.nih.gov/pubmed/10816502
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