Inhibition of Leukocyte Entry into the Brain by the Selectin Blocker Fucoidin Decreases Interleukin-1 (IL-1) Levels but Increases IL-8 Levels in Cerebrospinal Fluid during Experimental Pneumococcal Meningitis in Rabbits

The polysaccharide fucoidin is a selectin blocker that inhibits leukocyte recruitment into the cerebrospinal fluid (CSF) during experimental pneumococcal meningitis. In the present study, the effect of fucoidin treatment on the release of the proinflammatory cytokines tumor necrosis factor alpha (TN...

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Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Østergaard, Christian, Yieng-Kow, Runa Vavia, Benfield, Thomas, Frimodt-Møller, Niels, Espersen, Frank, Lundgren, Jens D.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2000
Matèries:	Host Response and Inflammation
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97550/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10816457/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.6.3153-3157.2000
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