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Immunoglobulin G3 Antibodies Specific for the 19-Kilodalton Carboxyl-Terminal Fragment of Plasmodium yoelii Merozoite Surface Protein 1 Transfer Protection to Mice Deficient in Fc-γRI Receptors

Merozoite surface protein 1 (MSP-1(19)) is a leading malaria vaccine candidate. Specific antibodies contribute to immunity; binding to macrophages is believed to represent the main action of malaria antibodies. We show that an MSP-1(19)-specific immunoglobulin G3 (IgG3) monoclonal antibody can passi...

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Udgivet i:Infect Immun
Principais autores: Vukovic, Peter, Hogarth, P. Mark, Barnes, Nadine, Kaslow, David C., Good, Michael F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97522/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10769007/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.5.3019-3022.2000
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