Inducible Expression of Human β-Defensin 2 by Fusobacterium nucleatum in Oral Epithelial Cells: Multiple Signaling Pathways and Role of Commensal Bacteria in Innate Immunity and the Epithelial Barrier

Human gingival epithelial cells (HGE) express two antimicrobial peptides of the β-defensin family, human β-defensin 1 (hBD-1) and hBD-2, as well as cytokines and chemokines that contribute to innate immunity. In the present study, the expression and transcriptional regulation of hBD-2 was examined....

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Krisanaprakornkit, Suttichai, Kimball, Janet R., Weinberg, Aaron, Darveau, Richard P., Bainbridge, Brian W., Dale, Beverly A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Host Response and Inflammation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97503/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10768988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.5.2907-2915.2000
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