Role of Manganese-Containing Superoxide Dismutase in Oxidative Stress and Virulence of Streptococcus pneumoniae

Streptococcus pneumoniae was shown to contain two types of superoxide dismutase, MnSOD and FeSOD. Levels of MnSOD increased during growth in an aerobic environment. The sodA gene, encoding MnSOD, of virulent S. pneumoniae type 2 strain D39 was inactivated to give mutant D39HY1. Aerobically, D39HY1 h...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Yesilkaya, Hasan, Kadioglu, Aras, Gingles, Neill, Alexander, Janet E., Mitchell, Tim J., Andrew, Peter W.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Molecular and Cellular Pathogenesis
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97493/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10768978/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.5.2819-2826.2000
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