Functional Flexibility of the FimH Adhesin: Insights from a Random Mutant Library

Type 1 fimbriae are surface organelles of Escherichia coli which mediate d-mannose-sensitive binding to different host surfaces. This binding is conferred by the minor fimbrial component FimH. Naturally occurring variants of the FimH protein have been selected in nature for their ability to recogniz...

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Bibliographic Details
Main Authors: Schembri, Mark A., Sokurenko, Evgeni V., Klemm, Per
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Molecular and Cellular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC97470/
https://ncbi.nlm.nih.gov/pubmed/10768955
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