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The sigA Gene Which Is Borne on the she Pathogenicity Island of Shigella flexneri 2a Encodes an Exported Cytopathic Protease Involved in Intestinal Fluid Accumulation

In this study, the sigA gene situated on the she pathogenicity island of Shigella flexneri 2a was cloned and characterized. Sequence analysis showed that sigA encodes a 139.6-kDa protein which belongs to the SPATE (serine protease autotransporters of Enterobacteriaceae) subfamily of autotransporter...

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Publicat a:Infect Immun
Autors principals: Al-Hasani, Keith, Henderson, Ian R., Sakellaris, Harry, Rajakumar, Kumar, Grant, Travis, Nataro, James P., Robins-Browne, Roy, Adler, Ben
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97446/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10768931/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.5.2457-2463.2000
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