Transforming Growth Factor-β Inhibits Lipopolysaccharide-Stimulated Expression of Inflammatory Cytokines in Mouse Macrophages through Downregulation of Activation Protein 1 and CD14 Receptor Expression

The septic shock that occurs in gram-negative infections is caused by a cascade of inflammatory cytokines. Several studies showed that transforming growth factor-β1 (TGF-β1) inhibits this septic shock through suppression of expression of the lipopolysaccharide (LPS)-induced inflammatory cytokines. I...

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Publicado en:	Infect Immun
Autores principales:	Imai, Kenichi, Takeshita, Akira, Hanazawa, Shigemasa
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2000
Materias:	Host Response and Inflammation
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10768925/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.5.2418-2423.2000
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